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CYC 116

Drug Profile

CYC 116

Alternative Names: CYC-116

Latest Information Update: 21 Apr 2016

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At a glance

  • Originator Cyclacel Pharmaceuticals
  • Class Antineoplastics; Pyrimidines; Small molecules
  • Mechanism of Action Aurora kinase A inhibitors; Aurora kinase B inhibitors; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Suspended Solid tumours

Most Recent Events

  • 16 Apr 2008 Preclinical pharmacodynamics data in Haematological malignancies presented at the 99th Annual Meeting of the American Association for Cancer Research (AACR-2008) ,
  • 27 Nov 2007 Interim efficacy and safety data from a phase I trial in solid tumours released by Cyclacel
  • 30 Jun 2007 Phase-I clinical trials in Solid tumours in USA (PO)
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