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Simeprevir - Medivir/Janssen R&D Ireland

Drug Profile

Simeprevir - Medivir/Janssen R&D Ireland

Alternative Names: Galexos; JNJ-38733214-AAA; Olysio; R-494617; SMV; Sovriad; TMC-435; TMC-435350

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Medivir AB
  • Developer Alios BioPharma; Janssen Pharmaceutical KK; Janssen R&D Ireland; Medivir AB
  • Class 3-ring heterocyclic compounds; Antivirals; Cyclopropanes; Quinolines; Small molecules; Sulfonamides; Thiazoles
  • Mechanism of Action Hepatitis C virus NS3 protein inhibitors; Hepatitis C virus NS4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hepatitis C

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 11 May 2018 Phase-II clinical trials in Hepatitis C (Combination therapy) in Mauritius, Moldova (PO) before May 2018 (NCT02569710)
  • 11 May 2018 Alios Biopharma completes a phase II trial in Hepatitis C in New Zealand, Moldova, Mauritius, United Kingdom (NCT02569710)
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