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Tafamidis meglumine - Pfizer

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Drug Profile

Tafamidis meglumine - Pfizer

Alternative Names: Fx-1006A; FX1006A; PF-06291826; PF-6291826; Tafamidis; Tafamidis free acid; VYNDAMAX; Vyndaqel; Vynmac

Latest Information Update: 18 May 2026

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At a glance

  • Originator FoldRx Pharmaceuticals
  • Developer Pfizer
  • Class Benzoxazoles; Carboxylic acids; Cardiovascular therapies; Chlorobenzenes; Neuroprotectants; Small molecules
  • Mechanism of Action Amyloid inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyloid polyneuropathy; Cardiomyopathies
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Amyloid polyneuropathy; Cardiomyopathies

Most Recent Events

  • 28 Apr 2026 Pfizer enters into an patent settlement agreement with Dexcel Pharma, Hikma Pharmaceuticals and Cipla to settle lawsuits filed for infringement of patents relating to Tafamidis
  • 23 Mar 2026 Pfizer initiates enrolment in a phase I trial for Healthy volunteers in Belgium (PO) (NCT07470866)
  • 19 Mar 2026 Pfizer plans a phase I bioequivalence trial (In volunteers) (PO, Capsule, Tablet) in March 2026 (NCT07470866)

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