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Tafamidis meglumine - Pfizer

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Drug Profile

Tafamidis meglumine - Pfizer

Alternative Names: Fx-1006A; FX1006A; PF-06291826; PF-6291826; Tafamidis; Tafamidis free acid; VYNDAMAX; Vyndaqel; Vynmac

Latest Information Update: 10 Jul 2026

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At a glance

  • Originator FoldRx Pharmaceuticals
  • Developer Pfizer
  • Class Benzoxazoles; Carboxylic acids; Cardiovascular therapies; Chlorobenzenes; Neuroprotectants; Small molecules
  • Mechanism of Action Amyloid inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cardiomyopathies; Amyloid polyneuropathy
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Amyloid polyneuropathy; Cardiomyopathies

Most Recent Events

  • 26 Jun 2026 Pfizer terminates a phase I trial for Healthy volunteers in Belgium (PO), due to business reasons; there were no safety concerns (NCT07470866)
  • 11 May 2026 Pfizer initiates enrolment in the phase I bioequivalence trial in Healthy volunteers in Japan (PO) (NCT07587697)
  • 11 May 2026 Pfizer plans a phase I trial in Healthy adult volunteers in Japan (PO, Tablet) (NCT07587697)

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