Tedizolid - Merck & Co

Drug Profile

Tedizolid - Merck & Co

Alternative Names: BAY 1192631; DA-70157; DA-70218; DA-7157; DA-7218; MK-1986; SIVEXTRO; Sivextro; Tedizolid phosphate; Torezolid; Torezolid phosphate; TR-700; TR-701; TR-701 FA; TR-701 free acid

Latest Information Update: 16 Oct 2018

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At a glance

  • Originator Dong-A Pharmaceutical
  • Developer Dong-A ST; Merck & Co
  • Class Antibacterials; Oxazolidinones; Skin disorder therapies; Small molecules
  • Mechanism of Action Ribosomal protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Skin and soft tissue infections
  • Phase III Nosocomial pneumonia
  • Phase I Gram-positive infections
  • No development reported Bacteraemia

Most Recent Events

  • 17 Sep 2018 Cubist Pharmaceuticals completes a phase III trial in Skin and soft tissue infections in Argentina, Bulgaria, Chile, Czech Republic, Georgia, Germany, Latvia, Lithuania, Panama, Poland, Romania, Slovenia, South Africa, Spain and in the US (NCT02276482)
  • 22 Jun 2018 Cubist completes a phase III trial in Nosocomial pneumonia in USA, Canada, Peru, South Africa, Australia, Georgia, Jordan, Lebanon, Russia, Ukraine, Belarus, Serbia, Greece, Latvia, Hungary, Austria, Brazil, Germany, Belgium, China, Czech Republic, France, Mexico, New Zealand, Puerto Rico, Taiwan, Thailand, Turkey, Guatemala, Japan, South Korea, Slovakia, Estonia, Croatia, Israel, South Korea, Spain, Philippines, Kazakhstan, Italy and Sri Lanka (IV) (NCT02019420)
  • 21 Apr 2018 Pooled pharmacokinetics data from a clinical study including patients from three phase I and two phase III trials in Skin and soft tissue infections presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases
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