Research programme: amyloid precursor protein secretase inhibitors - ArQule/Wyeth

Drug Profile

Research programme: amyloid precursor protein secretase inhibitors - ArQule/Wyeth

Alternative Names: Gamma secretase inhibitors - ArQule/Wyeth

Latest Information Update: 29 Mar 2012

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At a glance

  • Originator ArQule
  • Developer ArQule; Pfizer; Wyeth
  • Class Small molecules
  • Mechanism of Action Amyloid precursor protein secretase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No

Highest Development Phases

  • Discontinued Alzheimer's disease; Female genital diseases

Most Recent Events

  • 16 Oct 2009 Wyeth has been acquired by Pfizer
  • 31 May 2009 Discontinued - Preclinical for Alzheimer's disease in USA (unspecified route)
  • 20 Apr 2007 Preclinical development is ongoing for Alzheimer's disease
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