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Cantuzumab ravtansine

Drug Profile

Cantuzumab ravtansine

Alternative Names: C-242 DM4; C242 DM4 immunoconjugate; C242 maytansinoid-4 conjugate; huC242-DM4; IMGN-242; Maytasinoid DM4-conjugated humanised monoclonal antibody huC242; Monoclonal antibody C-242 DM4 conjugate

Latest Information Update: 15 Jun 2009

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At a glance

  • Originator ImmunoGen
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Maytansinoids; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Gastric cancer; Solid tumours

Most Recent Events

  • 12 Jun 2009 Discontinued - Phase-I for Solid tumours in USA (IV)
  • 12 Jun 2009 Discontinued - Phase-II for Gastric cancer in USA (IV)
  • 25 Oct 2007 Data presented at the 19th AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC-2007) added to the adverse events and Cancer therapeutic trials and pharmacodynamics sections ,
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