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Dovramilast - Amgen

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Drug Profile

Dovramilast - Amgen

Alternative Names: AMG-634; CC-11050

Latest Information Update: 08 Nov 2023

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At a glance

  • Originator Celgene Corporation
  • Developer Celgene Corporation; Medicines Development for Global Health
  • Class Amides; Anti-inflammatories; Cyclopropanes; Isoindoles; Small molecules
  • Mechanism of Action Type 4 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Leprosy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cutaneous lupus erythematosus; Leprosy; Tuberculosis

Most Recent Events

  • 03 Nov 2023 Dovramilast - Amgen receives Orphan Drug status for Leprosy in USA
  • 22 Dec 2020 AMG 634 licensed to Medicines Development for Global Health worldwide
  • 22 Jun 2020 Amgen plans phase II clinical trial in Tuberculosis in 2021

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