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Drug Profile


Alternative Names: CHR-1103; GBR 500; SAR 339658; TMC-2003; UNII-A4R7G50030

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Chromos Molecular Systems
  • Developer Glenmark Pharmaceuticals S.A.; Sanofi
  • Class Anti-inflammatories; Antirheumatics; Monoclonal antibodies
  • Mechanism of Action Angiogenesis inhibitors; Antibody-dependent cell cytotoxicity; Cell adhesion molecule inhibitors; Immunosuppressants; Integrin alpha2beta1 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Autoimmune disorders

Highest Development Phases

  • No development reported Cancer
  • Discontinued Chronic obstructive pulmonary disease; Multiple sclerosis; Retinal disorders; Rheumatoid arthritis; Ulcerative colitis

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 12 Jul 2016 Sanofi terminates a phase II/III trial in Multiple sclerosis based on the planned interim analysis (NCT02222948)
  • 01 Jan 2016 Vatelizumab is available for licensing as of 01 Jan 2016. http://www.glenmarkpharma.com/GLN_NWS/homepage.aspx?res=P_GLN
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