Larazotide - Alba Therapeutics

Drug Profile

Larazotide - Alba Therapeutics

Alternative Names: AT-1001 - Alba Therapeutics; INN-202; INN-217; Larazotide acetate; SPD 550

Latest Information Update: 20 Nov 2018

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At a glance

  • Originator University of Maryland School of Medicine
  • Developer Alba Therapeutics; Alba Therapeutics Corporation; Innovate Biopharmaceuticals; Teva Pharmaceutical Industries; University of Virginia School of Medicine
  • Class Anti-inflammatories; Antihyperglycaemics; Hepatoprotectants; Oligopeptides
  • Mechanism of Action Cell membrane permeability inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Non-alcoholic steatohepatitis

Highest Development Phases

  • Phase II Coeliac disease
  • Preclinical Non-alcoholic steatohepatitis
  • Research Gastrointestinal disorders
  • No development reported Crohn's disease; Irritable bowel syndrome
  • Discontinued Type 1 diabetes mellitus

Most Recent Events

  • 13 Nov 2018 Larazotide - Innovate Biopharmaceuticals is available for licensing as of 13 Nov 2018
  • 12 Nov 2018 Pharmacodynamics data from preclinical trials for Non-alcoholic steatohepatitis (NASH) released by Innovate Biopharmaceuticals
  • 31 Oct 2018 Innovate Biopharmaceuticals plans phase III trials for Coeliac disease (PO) in the first half of 2019 (PO, Capsule) (NCT03569007)
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