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Research programme: complement factor 5a inhibitors - Evolutec

Drug Profile

Research programme: complement factor 5a inhibitors - Evolutec

Latest Information Update: 19 Mar 2008

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At a glance

  • Originator Evolutec
  • Developer Case Western Reserve University; Evolutec
  • Class Recombinant proteins
  • Mechanism of Action Complement C5a inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Asthma; Autoimmune disorders; Guillain-Barre syndrome; Inflammation; Myasthenia gravis; Reperfusion injury

Most Recent Events

  • 31 Oct 2006 Preclinical trials in Asthma in United Kingdom (Parenteral)
  • 31 Oct 2006 Preclinical trials in Guillain-Barre syndrome in United Kingdom (Parenteral)
  • 29 May 2006 Case Western Reserve University has entered into an agreement with Evolutec to conduct further preclinical stuides of rEV 576 for myasthenia gravis
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