Rilpivirine - Janssen R&D Ireland

Drug Profile

Rilpivirine - Janssen R&D Ireland

Alternative Names: Edurant; G002 - Janssen Therapeutics; G007; G009-01; JNJ-16150108; Long-acting TMC278; R 278474; Rilpivirine hydrochloride; TMC 278; TMC278 LA (IM injection) - Tibotec; TMC278LA

Latest Information Update: 29 Aug 2018

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At a glance

  • Originator Tibotec Pharmaceuticals
  • Developer Janssen R&D Ireland; Janssen Therapeutics; PATH
  • Class Antiretrovirals; Nitriles; Pyrimidines; Small molecules
  • Mechanism of Action Non-nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HIV-1 infections

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 20 Jun 2018 Johnson & Johnson plans the phase III RISE trial for HIV-1 infections (Treatment-naive) in India (PO, Tablets), in July 2018 (NCT03563742)
  • 10 Apr 2018 Janssen Research & Development completes a phase I pharmacokinetics trial in Healthy volunteers in USA (IM, Controlled release) (NCT03127189)
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