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BMS 599626

Drug Profile

BMS 599626

Alternative Names: AC480; BMS599626

Latest Information Update: 18 Jun 2018

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer Ambit Biosciences Corporation; Bristol-Myers Squibb
  • Class Antineoplastics; Heterocyclic bicyclo compounds; Small molecules
  • Mechanism of Action Epidermal growth factor receptor antagonists; ERBB 2 receptor antagonists; ERBB 4 receptor antagonists; ERBB-3 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Breast cancer; Glioma; Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 23 Jul 2015 Discontinued - Phase-I for Breast cancer, Glioma, Non-small cell lung cancer and Solid tumours (Combination therapy) in USA after October 2013 (IV)
  • 22 Jun 2015 Ambit Biosciences withdraws phase-I trial in Solid tumours in USA prior to enrolment (Combination therapy) (NCT01245543)
  • 10 Nov 2014 Ambit Biosciences Corporation has been acquired by Daiichi Sankyo Company
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