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Fluocinolone acetonide micro-insert intravitreous implant - Alimera/EyePoint Pharmaceuticals

Drug Profile

Fluocinolone acetonide micro-insert intravitreous implant - Alimera/EyePoint Pharmaceuticals

Alternative Names: DF-277; FAI insert; Fluocinolone; Fluocinolone acetonide intravitreal implant; Fluocinolone acetonide intravitreal insert; Iluvien; Injectable micro-insert - Alimera Sciences/EyePoint Pharmaceuticals; Medidur implant; Medidur-FA; NSC-92339; Ophthalmic implant - Alimera Sciences/EyePoint Pharmaceuticals; YUTIQ

Latest Information Update: 18 Sep 2019

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At a glance

  • Originator pSivida Inc
  • Developer Alimera Sciences; EyePoint Pharmaceuticals; Hospital for Special Surgery; Johns Hopkins University; pSivida Inc; Specialised Therapeutics Australia
  • Class Anti-inflammatories; Antipruritics; Antirheumatics; Eye disorder therapies; Fluorinated steroids; Pregnadienes; Small molecules; Vasoconstrictors
  • Mechanism of Action Glucocorticoid receptor agonists; Nitric oxide synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes - Uveitis

Highest Development Phases

  • Marketed Diabetic macular oedema; Uveitis
  • Phase II Dry age-related macular degeneration; Retinal vascular occlusion; Wet age-related macular degeneration
  • Phase I Osteoarthritis

Most Recent Events

  • 17 Sep 2019 Alimera Sciences expands the distribution agreement with Horus Pharma for Diabetic macular oedema and Uveitis in Belgium, Netherlands, Luxembourg
  • 05 Aug 2019 Registered for Diabetic macular oedema in Australia (Intravitreous, Implant)
  • 30 Jul 2019 Updated efficacy and adverse events data from a phase III trial in Uveitis released by EyePoint Pharmaceuticals
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