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Fluocinolone acetonide - Alimera/EyePoint Pharmaceuticals

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Drug Profile

Fluocinolone acetonide - Alimera/EyePoint Pharmaceuticals

Alternative Names: DF-277; FAI insert; Fluocinolone; Fluocinolone acetonide intravitreal implant; Fluocinolone acetonide intravitreal insert; Fluocinolone acetonide micro-insert intravitreous implant - Alimera/EyePoint Pharmaceuticals; Iluvien; Injectable micro-insert - Alimera Sciences/EyePoint Pharmaceuticals; Medidur implant; Medidur-FA; NSC-92339; Ophthalmic implant - Alimera Sciences/EyePoint Pharmaceuticals; OT-401; OT-703; YUTIQ; YUTIQ50

Latest Information Update: 12 Aug 2024

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At a glance

  • Originator pSivida Inc
  • Developer Alimera Sciences; EyePoint Pharmaceuticals; Horus Pharma; Hospital for Special Surgery; Johns Hopkins University; Ocumension Therapeutics; pSivida Inc; Specialised Therapeutics Australia
  • Class Anti-inflammatories; Antipruritics; Antirheumatics; Eye disorder therapies; Fluorinated steroids; Pregnadienes; Small molecules; Vasoconstrictors
  • Mechanism of Action Glucocorticoid receptor agonists; Nitric oxide synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Diabetic macular oedema; Uveitis
  • Phase II Retinal vascular occlusion; Wet age-related macular degeneration
  • No development reported Osteoarthritis

Most Recent Events

  • 06 Aug 2024 Phase-III clinical trials in Uveitis (In adolescents, In adults, In children, Treatment-experienced) in Germany, United Kingdom (Intravitreous) (EudraCT2022-001622-29) (NCT06539481)
  • 08 Feb 2024 NICE issues final draft guidance recommending fluocinolone acetonide for Diabetic macular edema
  • 31 Dec 2023 Launched for Uveitis in United Arab Emirates (Intravitreous)

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