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Brivanib alaninate - ZAI Lab

Drug Profile

Brivanib alaninate - ZAI Lab

Alternative Names: BMS-540215; BMS-582664; Brivanib; ZL-2301

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer Bristol-Myers Squibb; Gynecologic Oncology Group; National Cancer Institute (USA); ZAI Lab
  • Class Antineoplastics; Esters; Indoles; Pyrroles; Small molecules; Triazines
  • Mechanism of Action Angiogenesis inhibitors; Type 1 fibroblast growth factor receptor antagonists; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Liver cancer
  • No development reported Solid tumours
  • Discontinued Cervical cancer; Colorectal cancer; Gastrointestinal cancer

Most Recent Events

  • 26 Sep 2018 Additional efficacy data from a phase II trial in Hepatocellular carcinoma released by Zai Lab
  • 26 Sep 2018 Zai Lab plans a trial for Hepatocellular carcinoma (Combination therapy) in China
  • 24 Jun 2018 Biomarkers information updated
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