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Research programme: receptor tyrosine kinase inhibitors - GlaxoSmithKline

Drug Profile

Research programme: receptor tyrosine kinase inhibitors - GlaxoSmithKline

Alternative Names: REarranged in Transfection tyrosine kinase inhibitors; GSK 1838705A; GW-578257A; RET inhibitors; RET tyrosine kinase inhibitors; VEGFR-2/TIE-2 inhibitors - GSK

Latest Information Update: 18 Apr 2011

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At a glance

  • Originator GlaxoSmithKline
  • Class Benzimidazoles; Small molecules
  • Mechanism of Action Anaplastic lymphoma kinase inhibitors; Insulin-like growth factor-I receptor antagonists; Receptor protein-tyrosine kinase antagonists; TIE 2 receptor antagonists; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 22 Apr 2009 Preclinical pharmacodynamics data on receptor tyrosine kinase inhibitors presented at the 100th Annual Meeting of the American Association for Cancer Research
  • 05 May 2005 Preclinical trials in Cancer in USA (unspecified route)
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