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Mavoglurant - STALICLA

Drug Profile

Mavoglurant - STALICLA

Alternative Names: AFQ-056; STP-7

Latest Information Update: 02 Dec 2024

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At a glance

  • Originator Novartis
  • Developer National Institute of Drug Abuse; Novartis; STALICLA
  • Class Alkynes; Antiparkinsonians; Anxiolytics; Drug withdrawal therapies; Esters; Indoles; Neuropsychotherapeutics; Nitriles; Small molecules
  • Mechanism of Action Metabotropic glutamate receptor 5 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Alcoholism
  • Phase I Cocaine-related disorders
  • Discontinued Anxiety disorders; Chorea; Drug-induced dyskinesia; Fragile X syndrome; Gastro-oesophageal reflux; Obsessive-compulsive disorders; Smoking withdrawal

Most Recent Events

  • 07 Oct 2024 Stalicla completes a phase I trial in Cocaine-related disorders (In volunteers, Treatment-naive) in USA (PO) (NCT06273540)
  • 01 Jul 2024 Phase-II clinical trials in Alcoholism in USA (PO) (NCT06136195)
  • 15 Apr 2024 Phase-I clinical trials in Cocaine-related disorders (In volunteers, Treatment-naive) in USA (PO) (NCT06273540)

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