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GDC 0152

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Drug Profile

GDC 0152

Alternative Names: GDC0152; IAP-antagonist - Genentech; IAP-inhibitor - Genentech; RG 7419; Second mitochondrial activator of caspases mimetics - Genentech; SMAC mimetics - Genentech

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Genentech
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Inhibitor of apoptosis protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cancer

Most Recent Events

  • 18 May 2007 Data presented at the 98th Annual Meeting of the American Association for Cancer Research (AACR-2007) added to the pharmacokinetics and Cancer pharmacodynamics sections
  • 08 Dec 2006 Data presented at the 18th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics (EORTC-NCI-AACR-2006) added to the Cancer pharmacodynamics section
  • 06 May 2005 Preclinical trials in Cancer in USA (unspecified route)

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