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RX 0301

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Drug Profile

RX 0301

Alternative Names: HC-0301; RX-0301; WGI-0301

Latest Information Update: 18 Sep 2025

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At a glance

  • Originator Rexahn Pharmaceuticals
  • Developer Rexahn Pharmaceuticals; Zhejiang Haichang Biotechnology
  • Class Antineoplastics; Antisense oligonucleotides
  • Mechanism of Action Proto-oncogene protein c-akt inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours
  • Preclinical Liver cancer
  • Discontinued Ovarian cancer; Pancreatic cancer; Renal cell carcinoma

Most Recent Events

  • 18 Sep 2025 RX 0301 is still in phase-I clinical trials in Solid tumours(Inoperable/Unresectable, Metastatic disease, Second-line therapy or greater, Late-stage disease) in USA (IV) (NCT05267899)
  • 22 Oct 2024 Ocuphire Pharma has merged with Opus Genetics to form Opus Genetics
  • 05 Apr 2024 Preclinical trials in Liver cancer in China (unspecified route) prior to April 2024

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