Navarixin - Ligand Pharmaceuticals/Merck & Co.
Alternative Names: MK-7123; PS-291822; SCH 527123; SCH 5271234Latest Information Update: 05 Nov 2023
At a glance
- Originator Pharmacopeia; Schering-Plough
- Developer Ligand Pharmaceuticals; Merck & Co
- Class Anti-inflammatories; Antineoplastics; Benzamides; Cyclobutanes
- Mechanism of Action Interleukin 8A receptor antagonists; Interleukin 8B receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Solid tumours
- Discontinued Asthma; Chronic obstructive pulmonary disease; Psoriasis
Most Recent Events
- 19 May 2021 Merck completes phase II trial in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA, Australia, Canada, South Korea, Israel (PO) (NCT03473925)
- 19 Feb 2021 Navarixin is still in phase II trial for Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA, Israel (PO) (NCT03473925)
- 22 Jan 2021 Merck & Co. completes enrolment in its phase II trial for Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA, Australia, Canada, Israel, South Korea (PO) (NCT03473925)