Drug Profile


Alternative Names: MK-7123; PS-291822; SCH 527123; SCH 5271234

Latest Information Update: 29 May 2015

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At a glance

  • Originator Pharmacopeia; Schering-Plough
  • Developer Ligand Pharmaceuticals; Merck & Co
  • Class Anti-inflammatories; Benzamides; Cyclobutanes
  • Mechanism of Action Interleukin 8A receptor antagonists; Interleukin 8B receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Asthma; Chronic obstructive pulmonary disease; Psoriasis

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 22 May 2013 Efficacy data from a phase II trial in Chronic obstructive pulmonary disease presented at the 109th International Conference of the American Thoracic Society (ATS-2013)
  • 01 Dec 2011 Merck terminates phase II trial in Chronic obstructive pulmonary disease in European Union, Russia, Ukraine, Australia, Canada, Mexico, Argentina, Chile, Peru and Venezuela (NCT01006616)
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