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Nadofaragene firadenovec - FKD Therapies

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Drug Profile

Nadofaragene firadenovec - FKD Therapies

Alternative Names: AAV-IFN-apha-2b-gene-therapy-FKD-Therapies; Adenovirus-Delivered Interferon Alpha-2b; Adstiladrin; FE-999326; Instiladrin; Nadofaragene firadenovec-vncg; Nadofaragene firadenovec/Syn3; rAd-IFNα; rAd-IFNα/Syn3; SCH-209702/SCH-721015; SCH-721015; SCH-721015/SCH-209702; TR-002

Latest Information Update: 23 Aug 2024

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At a glance

  • Originator Schering-Plough
  • Developer Ferring Pharmaceuticals; FKD Therapies; Trizell; University of Pennsylvania
  • Class Antineoplastics; IFNA2B gene therapies; Immunotherapies
  • Mechanism of Action Gene transference; IFNA2B expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Bladder cancer
  • Phase III Malignant-mesothelioma

Most Recent Events

  • 08 Aug 2024 Ferring Pharmaceuticals plans phase II ABLE-22 trial in Bladder cancer (Monotherapy, Combination therapy, Locally recurrent) in August 2024 (Intravesical, Infusion) (NCT06545955)
  • 29 Jul 2024 Ferring Pharmaceuticals plans a phase IIIb ABLE-32 trial for Bladder cancer in August 2024 (IV) (NCT06510374)
  • 06 May 2024 Efficacy and adverse events data from phase III trial in Bladder cancer released by Ferring Pharmaceuticals

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