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PSMA ADC - Progenics Pharmaceuticals

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Drug Profile

PSMA ADC - Progenics Pharmaceuticals

Alternative Names: Monomethylauristatin E-antiPSMA monoclonal antibody conjugate; PSMA Antibody Drug Conjugate

Latest Information Update: 18 Dec 2023

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At a glance

  • Originator PSMA Development Company
  • Developer Brown University; Progenics Pharmaceuticals; Rhode Island Hospital; University of Texas at Dallas
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Glioblastoma; Prostate cancer

Most Recent Events

  • 14 Dec 2023 Seagen has been acquired by Pfizer
  • 31 May 2023 Selexis has merged with KBI Biopharma to form KBI Biopharma
  • 08 Oct 2020 Seattle Genetics is now called Seagen

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