AFM 13

Drug Profile

AFM 13

Alternative Names: AFM-13; Anti CD30 x anti CD16; Anti-CD30 anti-CD16A antibody - Affimed Therapeutics; TandAb AFM13

Latest Information Update: 22 Mar 2018

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At a glance

  • Originator Affimed Therapeutics
  • Developer Affimed Therapeutics; Merck AG; The Leukemia & Lymphoma Society; University of Cologne; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Bispecific antibodies
  • Mechanism of Action CD30 antigen modulators; Fc gamma receptor IIIA modulators; Natural killer cell stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hodgkin's disease
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hodgkin's disease
  • Phase I/II Lymphoma
  • Preclinical Non-Hodgkin's lymphoma

Most Recent Events

  • 01 Mar 2018 Affimed therapeutics has patent protection for AFM 13 in USA, Australia, Canada, Japan and Europe
  • 01 Feb 2018 Interim efficacy data from phase I trial in Hodgkin's lymphoma (Combination therapy, Second-line therapy or greater) released by Affimed
  • 01 Feb 2018 Interim efficacy data from phase I/II trial in Lymphoma released by Affimed
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