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Research programme: cancer immunotherapeutics - PsiOxus Therapeutics

Drug Profile

Research programme: cancer immunotherapeutics - PsiOxus Therapeutics

Alternative Names: AbEnAds; anti-human VEGF armed EnAd; anti-PDL1 AbEnAds; NG 345; NG 347; NG 350a; NG 600; NG aEpCAM; NG aFAP; NG-600 series

Latest Information Update: 22 Nov 2018

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At a glance

  • Originator PsiOxus Therapeutics
  • Class Antibodies; Antineoplastics; Bispecific antibodies; Gene therapies; Oncolytic viruses
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T-lymphocyte antigen 4 inhibitors; Epithelial cell adhesion molecule inhibitors; Fibroblast activation protein antagonists; Gene transference; Immunomodulators; Immunostimulants; Programmed cell death-1 ligand-1 inhibitors; Vascular endothelial growth factors modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 15 Nov 2018 PsiOxus Therapeutics collaborates with the Parker Institute for cancer immunotherapy on virus-based gene therapy to treat Solid tumors
  • 18 Jul 2017 PsiOxus Therapeutics plans a phase I trial for NG 600 for Cancer (PsiOxus pipeline, January 2017).
  • 14 Apr 2016 PsiOxus Therapeutics and Parker Institute for Cancer enter into a memorandum of understaing for an anticipated collaboration using the Tumor-Specific Immuno-Gene Therapy (T-SIGn) platform developed by PsiOxus Therapeutics for Cancer
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