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Research programme: antibacterials - Vaxart

Drug Profile

Research programme: antibacterials - Vaxart

Alternative Names: Benzothiazole urea based inhibitors -Vaxart; CDI-538 series antibacterials - Prolysis; CDI-936 series antibacterials - Prolysis; GYR-767 series antibacterials - Prolysis; PC-190708; PC-190723

Latest Information Update: 16 Feb 2018

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At a glance

  • Originator Prolysis
  • Developer Aviragen Therapeutics
  • Class 2 ring heterocyclic compounds; Amides; Small molecules
  • Mechanism of Action Cell division inhibitors; DNA gyrase inhibitors; DNA topoisomerase IV inhibitors; Mitosis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Bacterial infections; Clostridium difficile infections; Pneumonia; Skin and soft tissue infections; Staphylococcal infections

Most Recent Events

  • 13 Feb 2018 Aviragen Therapeutics has merged with Vaxart forming Vaxart
  • 29 Jan 2018 Discontinued - Preclinical for Bacterial infections in Australia (IV)
  • 29 Jan 2018 Discontinued - Preclinical for Bacterial infections in Australia (PO)
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