Avibactam/ceftazidime - Allergan/Pfizer

Drug Profile

Avibactam/ceftazidime - Allergan/Pfizer

Alternative Names: AVE 1330/ceftazidime; AVE 1330A/ceftazidime; Avibactam/ceftazidime pentahydrate; AVYCAZ; CAZ 104; CAZ-AVI; Ceftazidime pentahydrate/avibactam; Ceftazidime/AVE 1330; Ceftazidime/AVE 1330A; Ceftazidime/NXL 104; NXL 104/ceftazidime; Zavicefta

Latest Information Update: 20 Jul 2018

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At a glance

  • Originator Novexel
  • Developer Allergan; AstraZeneca; Cerexa; Novexel; Pfizer
  • Class Amides; Antibacterials; Cephalosporins; Heterocyclic bicyclo compounds; Small molecules; Sulfates
  • Mechanism of Action Beta lactamase inhibitors; Cell wall inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Gram-negative infections; Intra-abdominal infections; Nosocomial pneumonia; Urinary tract infections

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 07 Jun 2018 Updated efficacy and adverse events data from the phase III REPROVE trial in Nosocomial pneumonia presented at the ASM Microbe 2018 (ASMM-2018)
  • 21 Apr 2018 Safety and efficacy data from a phase II trial in Intra-abdominal infections and Urinary tract infections presented at the Annual Meeting of the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID - 2018)
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