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Research programme: antibody-based cancer therapeutics - Affimed Therapeutics

Drug Profile

Research programme: antibody-based cancer therapeutics - Affimed Therapeutics

Alternative Names: AFM 12; AFM 18; AFM 20; AFM 21; AFM 22; AFM 24+; AFM 26; AFM 26+; AFM24_I; AFM24_T; anti CD19 x anti CD16; anti CD33 X anti CD3; anti-EGFRvIII/CD16A Tand AB; anti-EGFRvIII/CD3 TandAb; anti-EpCAM TandAb; Antibody-based non-Hodgkin's lymphoma therapeutics - Affimed; MHC-peptide complex antibody - Affimed; Trispecific Abs

Latest Information Update: 27 May 2019

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At a glance

  • Originator Affimed Therapeutics
  • Developer Affimed Therapeutics; Amphivena Therapeutics
  • Class Bispecific antibodies; Monoclonal antibodies; Trispecific antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Apoptosis stimulants; B-cell maturation antigen modulators; CD19 antigen modulators; CD200 antigen modulators; CD3 antigen modulators; CD33 antigen modulators; Epidermal growth factor receptor antagonists; Epithelial cell adhesion molecule inhibitors; Fc gamma receptor IIIA modulators; Immunomodulators; Major histocompatibility complex inhibitors; Matrix metalloproteinase 1 inhibitors; Natural killer cell stimulants; Phagocyte stimulants; T lymphocyte stimulants; T-lymphocyte differentiation antigen agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acute myeloid leukaemia; Cancer; Colorectal cancer; Head and neck cancer; Lung cancer; Solid tumours
  • No development reported Multiple myeloma; Non-Hodgkin's lymphoma

Most Recent Events

  • 01 Apr 2019 Preclinical development in Solid-tumours is ongoing in Germany (Parenteral)
  • 28 Feb 2019 No recent reports of development identified for preclinical development in Multiple-myeloma in Germany (Parenteral)
  • 08 Aug 2018 Affimed enters into a preclinical research collaboration with Nektar Therapeutics
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