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Debamestrocel - BrainStorm Cell Therapeutics

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Drug Profile

Debamestrocel - BrainStorm Cell Therapeutics

Alternative Names: Autologous bone marrow derived mesenchymal stem cell therapy - BrainStorm Cell therapeutics; Autologous MSC-NTF; Bone-marrow-derived-mesenchymal-stem-cells-BrainStorm; GDNF therapy; GDNf-stem-cell-therapy-BrainStorm-Cell-Therapeutics; Glial-cell-line-derived-neurotrophic-factor-producing-adult-bone-marrow-derived-stem-cell-therapy-BrainStorm Cell Therapeutics; Glial-cell-line-derived-neurotrophic-factor-stem-cell-therapy-BrainStorm; MSC-NTF; MSC-NTF cell; MSC-NTF-BrainStorm-Cell-Therapeutics; Neurotrophic factor-producing mesenchymal stem cell therapy - BrainStorm Cell Therapeutics; Neurotrophic factor-secreting stem cell therapy; Neurotrophic-factor-producing-adult-stem-cell-therapy-BrainStorm; NurOwn; NurOwn-GDNF-therapy; NurOwn™ program one

Latest Information Update: 23 May 2024

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At a glance

  • Originator Tel Aviv University
  • Developer Brainstorm Cell Therapeutics; Hadassah Medical Organization; Tel Aviv University
  • Class Exosome therapies; Mesenchymal stem cell therapies; Stem cell therapies
  • Mechanism of Action Dopaminergic cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Alzheimer's disease; Amyotrophic lateral sclerosis; Multiple sclerosis
  • Preclinical Acute lung injury; Huntington's disease; Parkinson's disease; Peripheral nerve injuries; Pervasive child development disorders
  • No development reported Sciatica; Spinal cord injuries

Most Recent Events

  • 20 May 2024 Pharmacodynamics data from a an expanded-access programme for Amyotrophic lateral sclerosis released by Brainstorm Cell Therapeutics
  • 09 Apr 2024 BrainStorm Cell Therapeutics receives agreement under special protocol assessment from the FDA for neurotrophic factor producing mesenchymal stem cell therapy in Amyotrophic lateral sclerosis
  • 09 Apr 2024 Brainstorm Cell Therapeutics plans a phase IIIb trial for Amyotrophic lateral sclerosis in 2024
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