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Otilimab - GlaxoSmithKline

Drug Profile

Otilimab - GlaxoSmithKline

Alternative Names: GSK-3196165; GSK165; MOR-103

Latest Information Update: 12 Jul 2020

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At a glance

  • Originator MorphoSys
  • Developer GlaxoSmithKline; MorphoSys
  • Class Anti-inflammatories; Antirheumatics; Monoclonal antibodies
  • Mechanism of Action Granulocyte macrophage colony stimulating factor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Rheumatoid arthritis
  • Phase II Severe acute respiratory syndrome
  • No development reported Inflammation
  • Discontinued Multiple sclerosis; Osteoarthritis

Most Recent Events

  • 24 Jun 2020 GlaxoSmithKline re-initiates enrolment in its previously-suspended phase III contRAst-3 trial in Rheumatoid arthritis (Combination therapy, Treatment-experienced) in the US, Argentina, Belgium, Canada, Czech Republic, Hungary, Italy, Japan, South Korea, South Africa, Poland, Lithuania, Spain and United Kingdom (NCT04134728) (EudraCT2019-000868-18)
  • 24 Jun 2020 GlaxoSmithKline re-initiates enrolment in its previously suspended phase III contRAst-1 trial in Rheumatoid arthritis (Combination therapy, Treatment-experienced) in the US, Argentina, Canada, Czech Republic, Hungary, India, Italy, Latvia, Lithuania, Malaysia, Poland, Russia, South Africa, Spain, Ukraine and United Kingdom (SC) (NCT03980483) (EudraCT2019-000797-39)
  • 22 Jun 2020 GlaxoSmithKline re initiates the phase III contRAst-2 trial in Rheumatoid arthritis in the US, Argentina, Bulgaria, Colombia, Estonia, France, Hungary, Japan, South Korea, Poland, Russia, Spain, Germany, Australia and United Kingdom (NCT03970837) (EudraCT2019-000867-26)
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