Drug Profile


Alternative Names: Artekin; Eurartekin; Eurartesim; Piperaquine/dihydroartemisinin

Latest Information Update: 03 Dec 2015

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At a glance

  • Originator Chongqing Holley; Medicines for Malaria Venture; sigma-tau SpA; University of Oxford
  • Developer Medicines for Malaria Venture; sigma-tau SpA
  • Class Antimalarials; Artemisinins; Piperazines; Quinolines; Sesquiterpenes
  • Mechanism of Action Free radical stimulants; Hemozoin inhibitors; Sarcoplasmic reticulum calcium-transporting ATPase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Malaria
  • New Molecular Entity No

Highest Development Phases

  • Marketed Malaria

Most Recent Events

  • 03 Dec 2015 The Medicines for Malaria Venture announces intention to submit the dispersible paediatric formulation to the EMA in the second quarter of 2015
  • 08 Jul 2015 Sigma-tau SpA completes its phase II trial in Malaria (In infants) in Tanzania, Congo, Mozambique, Gambia and Burkina Faso (NCT01992900)
  • 02 Jul 2015 Dihydroartemisinin/piperaquine licensed to Pierre Fabre in Angola, Benin, Botswana, Burkina Faso, Burundi, Cameroon, Chad, Congo, Democratic Republic of the Congo, Ethiopia, Gabon, Ghana, Guinea, Ivory Coast, Kenya, Liberia, Madagascar, Malawi, Mali, Mauritania, Mozambique, Namibia, Niger, Nigeria, Senegal, Sierra Leone, Swaziland, Tanzania, Togo, Uganda, Zambia and Zimbabwe
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