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Brimapitide - Altamira Therapeutics/Xigen

Drug Profile

Brimapitide - Altamira Therapeutics/Xigen

Alternative Names: AM-111; AM111 peptide; D-JNKI-1; Sonsuvi; XG-102; XG102 peptide

Latest Information Update: 06 Jun 2023

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At a glance

  • Originator Xigen
  • Developer Altamira Therapeutics; ribOvax Biotechnologies; Xigen
  • Class Anti-inflammatories; Antidementias; Cardiovascular therapies; Eye disorder therapies; Neuroprotectants; Peptides; Urologics
  • Mechanism of Action Mitogen-activated protein kinase 8 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sensorineural hearing loss
  • New Molecular Entity Yes
  • Available For Licensing Yes - Hearing loss

Highest Development Phases

  • Phase III Ocular inflammation
  • Suspended Sensorineural hearing loss
  • No development reported Alzheimer's disease; Eye disorders; Interstitial cystitis; Kidney disorders; Stroke
  • Discontinued Ear disorders; Myocardial infarction; Parkinson's disease; Transplant rejection

Most Recent Events

  • 16 May 2023 Suspended - Phase-II for Sensorineural hearing loss in Poland (Intratympanic) prior to May 2023
  • 16 May 2023 Suspended - Phase-III for Sensorineural hearing loss in Canada, USA, South Korea, Asia, Czech Republic, Hungary, Spain, Bulgaria, Germany (Intratympanic) prior to May 2023
  • 16 May 2023 Suspended - Preclinical for Sensorineural hearing loss in Japan (Intratympanic) prior to May 2023
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