Rexlemestrocel-L - Mesoblast/Teva Pharmaceutical Industries

Drug Profile

Rexlemestrocel-L - Mesoblast/Teva Pharmaceutical Industries

Alternative Names: Allogeneic mesenchymal precursor cells - Mesoblast; Allogeneic STRO-3 immunoselected bone marrow-derived mesenchymal precursor cells (MPCs) - Mesoblast; CEP-41750; Mesenchymal stem cell therapy - Mesoblast; MPC 06; MPC-06-ID; MPC-150; MPC-150-IM; MPC-25; MPC-25-IC; MPC-300; MPC-300-IV; MPC-75-IA; MPC-CBE; MPC-MICRO-IO; MSB-CAR001; NeoFuse; Replicart; Revascor

Latest Information Update: 17 Apr 2018

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At a glance

  • Originator Hanson Institute; Institute of Medical and Veterinary Science
  • Developer Angioblast Systems; Mesoblast; Teva Pharmaceutical Industries
  • Class Anti-inflammatories; Antihypercalcaemics; Antineoplastics; Antirheumatics; Heart failure therapies; Skin disorder therapies; Stem cell therapies
  • Mechanism of Action Cell replacements; Osteogenesis stimulants; Tissue replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Haematological malignancies
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Acute myeloid leukaemia; Heart failure; Intervertebral disc degeneration; Non-Hodgkin's lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma
  • Phase II Myocardial infarction; Osteoarthritis; Rheumatoid arthritis; Spondylosis; Type 2 diabetes mellitus
  • Phase I/II Diabetic nephropathies
  • Preclinical Age-related macular degeneration; Lung disorders
  • No development reported Fracture; Peripheral arterial disorders; Skin ulcer

Most Recent Events

  • 28 Mar 2018 Mesoblast completes enrolment in its phase III trial for Intervertebral disc degeneration in Australia and the US
  • 21 Dec 2017 Rexlemestrocel-L - Mesoblast/Teva Pharmaceutical Industries receives Regenerative Medicine Advanced Therapy designation for Heart failure in USA
  • 15 Dec 2017 Mesoblast completes enrolment in its phase IIb trial for Heart failure in USA
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