Paclitaxel oral - Athenex

Drug Profile

Paclitaxel oral - Athenex

Alternative Names: Oral paclitaxel - Hanmi Pharmaceutical; Oraxol; Paclitaxel/HM 30181A

Latest Information Update: 27 Jun 2018

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At a glance

  • Originator Hanmi Pharmaceutical
  • Developer Athenex; Hanmi Pharmaceutical; PharmaEssentia Corporation; Zenith Technology Corporation
  • Class Antineoplastics; Diterpenes; Paclitaxels; Small molecules; Taxanes
  • Mechanism of Action Angiogenesis inhibitors; Mitosis inhibitors; P-glycoprotein inhibitors; Platelet-derived growth factor inhibitors; Proto-oncogene protein c-bcl-2 inhibitors; Tubulin inhibitors; Tubulin polymerisation promoters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Haemangiosarcoma
  • New Molecular Entity No

Highest Development Phases

  • Phase III Breast cancer
  • Phase II Cancer; Gastric cancer
  • Phase I Oesophageal cancer; Solid tumours

Most Recent Events

  • 17 Jul 2018 Athenex plans a phase I trial for Solid tumours (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in USA (PO), (NCT03588039)
  • 27 Jun 2018 Athenex initiates enrolment in a clinical trial for Breast-cancer in Asia, Pacific rim countries (KX-ORAX-008) (Athenex pipeline June 2018)
  • 08 Jun 2018 Athenex plans a phase I trial for Haemangiosarcoma (Late-stage disease, Recurrent, In adults, In the elderly) in USA and Hong Kong in July 2018 (NCT03544567)
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