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Tonogenchoncel-L - Kolon TissueGene

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Drug Profile

Tonogenchoncel-L - Kolon TissueGene

Alternative Names: Invossa; Invossa K Inj.; Invossa K Injection; INVOSSA-K inj; TG C; TGF-beta-1 gene therapy - Kolon TissueGene; TissueGene-C; TissueGene-C(S); Transforming growth factor-beta-1 gene therapy - Kolon TissueGene

Latest Information Update: 04 Aug 2026

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At a glance

  • Originator TissueGene
  • Developer Kolon Life Science; Kolon TissueGene
  • Class Cell therapies; Gene therapies
  • Mechanism of Action Chondrocytes replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Osteoarthritis
  • Preclinical Intervertebral disc degeneration
  • No development reported Rheumatoid arthritis

Most Recent Events

  • 20 Jul 2026 Efficacy and adverse event data from a phase III ACTiVION-II trial in Osteoarthritis released by Kolon TissueGene
  • 01 May 2026 Kolon TissueGene completes a phase III trial in Osteoarthritis in USA (NCT03291470)
  • 01 Dec 2025 Mitsubishi Tanabe Pharma Corporation is now called Tanabe Pharma Corporation

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