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Clostridium butyricum M588- Miyarisan Pharmaceutical

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Drug Profile

Clostridium butyricum M588- Miyarisan Pharmaceutical

Alternative Names: Clostridium butyricum Miyairi 588 strain; C. butyricum CBM 588 Probiotic Strain; C. butyricum MIYAIRI Strain; C. butyricum Strain MIYAIRI 588; CBM-588; Cdactin-O; CM588; Miya-BM; MIYAIRI 588 Strain of C. butyricum

Latest Information Update: 28 Feb 2026

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At a glance

  • Originator Miyarisan Pharmaceutical
  • Developer Miyarisan Pharmaceutical; Osel Inc
  • Class Antidiarrhoeals; Antineoplastics; Probiotics
  • Mechanism of Action Gastrointestinal microbiome modulators; Neutrophil stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Diarrhoea
  • Phase I Renal cancer
  • No development reported Renal cell carcinoma

Most Recent Events

  • 28 Feb 2026 No recent reports of development identified for phase-I development in Renal-cell-carcinoma(Combination therapy, Late-stage disease, Metastatic disease) in USA (PO)
  • 08 Jan 2026 Osel Inc and SWOG Cancer Research Network enter into clinical trial agreement for Renal cell carcinoma
  • 08 Jan 2026 Miyarisan Pharmaceutical has patent protection for Clostridium butyricum M588

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