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Alternative Names:
ASP 1517; AZD 9941; Evrenzo; FG-4592
Latest Information Update: 17 Jun 2020
Price :
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At a glance
Originator
FibroGen
Developer
Astellas Pharma; AstraZeneca; FibroGen
Class
Amides; Antianaemics; Carboxylic acids; Isoquinolines; Small molecules
Mechanism of Action
Hypoxia-inducible factor-proline dioxygenase inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
No
New Molecular Entity
Yes
Highest Development Phases
Marketed
Anaemia
Phase II
Chemotherapy-induced anaemia
Discontinued
Sickle cell anaemia
Most Recent Events
12 Jun 2020
Efficacy data from the phase III DOLOMITES trial in Anaemia (in chronic kidney disease patients not on dialysis) presented at the European Renal Association – European Dialysis and Transplant Association (ERA-EDTA)
08 Jun 2020
Efficacy and adverse events data from the phase III DOLOMITES trial in Anaemia (in chronic kidney disease patients not on dialysis) presented at the 57th European Renal Association – European Dialysis and Transplant Association (ERA-EDTA)
01 Jun 2020
Fibrogen in collaboration with AstraZeneca plans a phase IIIb trial for Anaemia (NCT04410198)
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