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Research programme: antioxidant inflammation modulators - Biogen

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Drug Profile

Research programme: antioxidant inflammation modulators - Biogen

Alternative Names: AIMs - Biogen; CDDO-Im; Nrf2 activators - Biogen; RTA 403; RTA 404; RTA dh404; RTA-411; Synthetic triterpenoids - Biogen; TBEs - Biogen/Abbott; Tricyclic bis-enones - Biogen

Latest Information Update: 27 Sep 2023

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At a glance

  • Originator Dartmouth College; University of Texas M. D. Anderson Cancer Center
  • Developer Biogen
  • Class 3-ring heterocyclic compounds; Anti-inflammatories; Antineoplastics; Ketones; Neuroprotectants; Triterpenes
  • Mechanism of Action NF-E2-related factor 2 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Autoimmune disorders; Brain disorders; Cancer; Chronic obstructive pulmonary disease

Most Recent Events

  • 26 Sep 2023 Reata Pharmaceuticals has been acquired and merged into Biogen
  • 28 Oct 2021 No recent reports of development identified for preclinical development in Autoimmune-disorders in USA (PO)
  • 28 Oct 2021 No recent reports of development identified for preclinical development in Brain-disorders in USA

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