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Research programme: p53-HDM2 inhibitors - Ascenta Therapeutics

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Drug Profile

Research programme: p53-HDM2 inhibitors - Ascenta Therapeutics

Alternative Names: MI-147; MI-219; MI-43; MI-519-64; MI-63

Latest Information Update: 16 Jul 2016

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At a glance

  • Originator University of Michigan
  • Developer Ascenta Therapeutics
  • Class Small molecules
  • Mechanism of Action Apoptosis stimulants; Proto-oncogene protein c-mdm2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No

Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 16 Jul 2016 No recent reports of development identified for preclinical development in Cancer in USA (PO)
  • 04 Jun 2010 Drug candidates from the research programme licensed to sanofi-aventis worldwide ,
  • 11 Dec 2007 Pharmacodynamics data from a preclinical study in cancer presented at the 49th Annual Meeting and Exposition of the American Society of Hematology (ASH-2007)

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