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Varlitinib - Array BioPharma/ASLAN Pharmaceuticals

Drug Profile

Varlitinib - Array BioPharma/ASLAN Pharmaceuticals

Alternative Names: ARRY-334543; ARRY-543; ASLAN-001; QBT-01; SPS-4370; Varlitinib tosylate

Latest Information Update: 15 Jan 2019

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At a glance

  • Originator Array BioPharma
  • Developer Array BioPharma; ASLAN Pharmaceuticals
  • Class Antineoplastics; Diamines; Oxazoles; Quinazolines; Small molecules; Thiazoles
  • Mechanism of Action Epidermal growth factor receptor antagonists; ERBB 2 receptor antagonists; ERBB 4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Biliary cancer; Cholangiocarcinoma; Gastric cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Biliary cancer
  • Phase II/III Gastric cancer
  • Phase II Breast cancer; Cholangiocarcinoma
  • Phase I Solid tumours
  • Clinical Phase Unknown Liver cancer

Most Recent Events

  • 14 Jan 2019 Safety and efficacy data from a phase II/III trial in Gastric cancer released by ASLAN Pharmaceuticals
  • 02 Jan 2019 ASLAN Pharmaceuticals intends to submit an NDA to the US FDA for an accelerated approval in second-line Biliary cancer
  • 02 Jan 2019 ASLAN Pharmaceuticals completes enrolment in its TreeTopp phase II/III trial for Biliary cancer in USA, South Korea, Europe, China, Japan, Australia, and Singapore (NCT03093870)
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