Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

Sepantronium bromide

Next Previous
Drug Profile

Sepantronium bromide

Alternative Names: YM-155; YM155 monobromide

Latest Information Update: 28 Jun 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Astellas Pharma
  • Class Antineoplastics; Naphthoquinones; Small molecules
  • Mechanism of Action BIRC5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Solid tumours
  • Discontinued Breast cancer; Diffuse large B cell lymphoma; Malignant melanoma; Non-Hodgkin's lymphoma; Non-small cell lung cancer; Prostate cancer

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in Solid-tumours in USA (IV, Infusion)
  • 25 Apr 2025 Pharmacodynamics data from a preclinical trial in Ovarian cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 13 May 2022 Pharmacodynamics data from a preclinical trial in Renal cell carcinoma presented at the 117th Annual Meeting of the American Urological Association

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top