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Genistein nanoparticle - Humanetics Corporation

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Drug Profile

Genistein nanoparticle - Humanetics Corporation

Alternative Names: BIO-300

Latest Information Update: 28 Feb 2025

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At a glance

  • Originator Armed Forces Radiobiology Research Institute; National Institutes of Health (USA); United States Department of Defense
  • Developer Armed Forces Radiobiology Research Institute; Henry Ford Health System; Humanetics Corporation; Medical College of Wisconsin; Milwaukee VA Medical Center; National Institutes of Health (USA); University of Maryland, Baltimore
  • Class Antifibrotics; Antineoplastics; Chemosensitisers; Isoflavones; Osteoporosis therapies; Phytotherapies; Radioprotectives; Small molecules
  • Mechanism of Action Antioxidants; Apoptosis inhibitors; Apoptosis stimulants; Cell cycle modulators; DNA repair enzyme modulators; Haematopoietic cell growth factor stimulants; Inflammation mediator modulators; Protein tyrosine kinase inhibitors; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute radiation syndrome
  • New Molecular Entity No

Highest Development Phases

  • Phase II Pulmonary fibrosis
  • Phase I/II Radiation injuries
  • No development reported Acute radiation syndrome

Most Recent Events

  • 28 Feb 2025 No recent reports of development identified for phase-I development in Acute-radiation-syndrome(In volunteers, In adults) in USA (PO, Powder)
  • 28 Feb 2025 No recent reports of development identified for phase-I development in Acute-radiation-syndrome(Prevention) in USA (PO, Capsule)
  • 28 Feb 2025 No recent reports of development identified for phase-I development in Radiation-injuries(Combination therapy, Prevention) in USA (PO)

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