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Research programme: anticancer therapies - Moleculin Biotech/University of Texas M D Anderson Cancer Center

Drug Profile

Research programme: anticancer therapies - Moleculin Biotech/University of Texas M D Anderson Cancer Center

Alternative Names: 2-DG prodrug; CP2005; Degrasyns; Tyrphostins; WP 1122; WP 1234; WP 1732; WP1106; WP1129; WP1130

Latest Information Update: 10 Apr 2019

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At a glance

  • Originator University of Texas M. D. Anderson Cancer Center
  • Developer Jagiellonian University; Moleculin; Moleculin Biotech
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Apoptosis stimulants; Bcr-abl tyrosine kinase inhibitors; Glycolysis inhibitors; Janus kinase-2 inhibitors; STAT3 transcription factor inhibitors; Ubiquitin protein ligase complex modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer; Glioblastoma; Pancreatic cancer
  • Research Eye neoplasms

Most Recent Events

  • 14 May 2019 Moelculin Biotech announces intention to submit IND application to the US FDA for WP 1122 for Pancreatic cancer in 2020
  • 14 May 2019 Moleculin Biotech announces intention to submit an IND application for WP 1732 to the US FDA for Pancreatic cancer in fourth quarter of 2019
  • 14 May 2019 Moelculin Biotech plans a phase I trial for WP 1732 in 2020
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