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Retosiban - GlaxoSmithKline

Drug Profile

Retosiban - GlaxoSmithKline

Alternative Names: 221149; GSK-221149; GSK-221149A

Latest Information Update: 04 Oct 2019

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At a glance

  • Originator GlaxoSmithKline
  • Class Indenes; Morpholines; Oxazoles; Piperazines; Small molecules; Tocolytics
  • Mechanism of Action Oxytocin receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Preterm labour

Most Recent Events

  • 02 Sep 2019 GlaxoSmithKline completes the phase III ARIOS trial in Preterm labour in France, Spain, Belgium, Germany, Israel, Italy, Japan, Mexico, South Korea, Sweden, United Kingdom and USA (IV) (NCT02292784)
  • 24 Jun 2018 Biomarkers information updated
  • 20 Oct 2017 GlaxoSmithKline terminates a phase III trial in Preterm labour in Israel, Belgium, Germany, South Korea, Italy, Spain, Sweden, France, Mexico due to feasibility of recruiting the study in a timely manner (IV) (NCT02292771)
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