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Gevokizumab - Novartis

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Drug Profile

Gevokizumab - Novartis

Alternative Names: S-78989; VPM 087; XMA-005.2; XMA-0052; XOMA-052

Latest Information Update: 28 Feb 2026

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At a glance

  • Originator XOMA
  • Developer IRIS; National Eye Institute; North Shore-Long Island Jewish Health System; Novartis; Servier; University of Zurich; XOMA
  • Class Anti-inflammatories; Antiacnes; Antigouts; Antihyperglycaemics; Antineoplastics; Antirheumatics; Cardiovascular therapies; Eye disorder therapies; Immunotherapies; Monoclonal antibodies; Skin disorder therapies; Vascular disorder therapies
  • Mechanism of Action Interleukin 1 beta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pyoderma; Uveitis; Behcet's syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Colorectal cancer; Gastric cancer; Oesophageal cancer; Renal cell carcinoma
  • Discontinued Acne vulgaris; Acute coronary syndromes; Diabetic nephropathies; Giant cell arteritis; Gout; Juvenile rheumatoid arthritis; Labyrinthitis; Myositis; Osteoarthritis; Pyoderma; Rheumatoid arthritis; Schnitzler syndrome; Scleritis; Type 1 diabetes mellitus; Type 2 diabetes mellitus; Uveitis

Most Recent Events

  • 28 Feb 2026 No recent reports of development identified for phase-I development in Colorectal-cancer(Combination therapy, First-line therapy, Metastatic disease) in Australia (IV)
  • 28 Feb 2026 No recent reports of development identified for phase-I development in Colorectal-cancer(Combination therapy, First-line therapy, Metastatic disease) in Belgium (IV)
  • 28 Feb 2026 No recent reports of development identified for phase-I development in Colorectal-cancer(Combination therapy, First-line therapy, Metastatic disease) in Canada (IV)

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