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Drug Profile

Research programme: neurodegenerative disorders therapeutics - CombinatoRx

Latest Information Update: 22 Sep 2010

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At a glance

Originator CHDI; Zalicus
Developer CHDI; CombinatoRx; Zalicus
Class
Mechanism of Action Survival of motor neuron 1 protein stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No

Highest Development Phases

Discontinued Huntington's disease; Spinal muscular atrophy

Most Recent Events

31 Dec 2007 Discontinued - Preclinical for Spinal muscular atrophy in USA (unspecified route)
21 May 2007 Lead identification is ongoing
31 Aug 2005 Preclinical trials in Huntington's disease in USA (unspecified route)

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