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Irinotecan-eluting beads - Biocompatibles

Drug Profile

Irinotecan-eluting beads - Biocompatibles

Alternative Names: CM-BC2; DEBIRI; Irinotecan bead; Irinotecan-loaded DC Bead LUMI™; Irinotecan-loaded DC BeadM1™; Irinotecan-loaded DC Bead™; PARAGON Bead

Latest Information Update: 21 Aug 2019

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At a glance

  • Originator Biocompatibles International
  • Developer Biocompatibles International; BTG; Singapore General Hospital
  • Class Alkaloids; Antineoplastics; Camptothecins; Small molecules
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma
  • New Molecular Entity No

Highest Development Phases

  • Marketed Colorectal cancer; Liver metastases
  • Phase II Cholangiocarcinoma
  • Phase I/II Glioma

Most Recent Events

  • 19 Aug 2019 BTG has been acquired by Boston Scientific Corporation
  • 19 Oct 2018 Safety and efficacy data from a phase II trial in Colorectal cancer with liver metastases presented at the 43rd European Society for Medical Oncology Congress (ESMO-2018) (NCT01839877)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Colorectal-cancer(Late-stage disease, Refractory metastatic disease, Second-line therapy or greater) in Singapore (Intra-arterial)
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