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Eftilagimod alpha - Immutep Limited

Drug Profile

Eftilagimod alpha - Immutep Limited

Alternative Names: EDP-202; Efti; EOC-202; hLAG-3Ig; ImmuFact IMP321; ImmuFact-IMP321; IMP-321; LAG-3-Ig-fusion-protein; LAG-3Ig; sLAG-3-Ig

Latest Information Update: 18 Oct 2019

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At a glance

  • Originator Immutep
  • Developer EOC Pharma; Immutep; Immutep Limited; Krankenhaus Nordwest; Merck & Co; Prima BioMed
  • Class Adjuvants; Antineoplastics; CD antigens; Immunoglobulins; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Antigen presenting cell stimulants; Cytotoxic T lymphocyte stimulants; Dendritic cell stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Breast cancer

Highest Development Phases

  • Phase II Breast cancer; Non-small cell lung cancer; Squamous cell cancer
  • Phase I Malignant melanoma; Solid tumours
  • No development reported Renal cell carcinoma

Most Recent Events

  • 15 Oct 2019 Final efficacy data from a phase I trial in Malignant melanoma released by Immutep (NCT02676869)
  • 26 Sep 2019 Interim efficacy data from the phase II TACTI-002 trial in Non-small cell lung cancer released by Immutep
  • 23 Aug 2019 Immutep has patent protection for Eftilagimod alpha in Europe
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