Eftilagimod alpha - Immutep Limited

Drug Profile

Eftilagimod alpha - Immutep Limited

Alternative Names: EDP-202; Efti; EOC202; hLAG-3Ig; ImmuFact IMP321; IMP321; LAG-3-Ig-fusion-protein; LAG-3Ig; sLAG-3-Ig

Latest Information Update: 14 Aug 2018

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At a glance

  • Originator Immutep
  • Developer Immutep; Immutep Limited; Krankenhaus Nordwest; Prima BioMed
  • Class Adjuvants; Antineoplastics; CD antigens; Immunoglobulins; Recombinant fusion proteins
  • Mechanism of Action Antigen presenting cell stimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Breast cancer

Highest Development Phases

  • Phase II Breast cancer
  • Phase I Malignant melanoma; Solid tumours
  • No development reported Renal cell carcinoma

Most Recent Events

  • 08 Aug 2018 EOC Pharma plans clinical trial for eftlagimod in combination with paclitaxel in Metastatic breast cancer in third quarter of 2018 in China
  • 07 Aug 2018 Immutep Limited completes enrolment in the phase I TACTI-mel trial for Malignant melanoma (Adjunctive treatment, Inoperable/Unresectable, Metastatic disease, Second-line therapy or greater) in Australia
  • 31 Jul 2018 Updated efficacy data from phase I TACTI-Mel trial in Malignant melanoma released by Immuntep
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