Research programme: systemic RNAi therapeutics - Alnylam/Arbutus Biopharma

Drug Profile

Research programme: systemic RNAi therapeutics - Alnylam/Arbutus Biopharma

Alternative Names: TKM-ALDH2

Latest Information Update: 04 Apr 2018

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At a glance

  • Originator Alnylam Pharmaceuticals; Tekmira Pharmaceuticals Corporation
  • Developer Alnylam Pharmaceuticals; Arbutus Biopharma
  • Class RNA
  • Mechanism of Action Aldehyde dehydrogenase 2 inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Alcoholism; Cancer

Most Recent Events

  • 16 Mar 2018 Arbutus has issued and pending patents for its therapeutic HBV product candidates and LNP delivery technology in countries worldwide
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Alcoholism in Canada (Parenteral)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Cancer in Canada (IV)
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